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DBCO-Gly-Gly-Gly

Product Sizes
10 mg
£341.00
CCT-1551-10MG
25 mg
£639.00
CCT-1551-25MG
100 mg
£2117.00
CCT-1551-100MG
About this Product
SKU:
CCT-1551
Application:
Conjugation/Labeling
Conjugate:
DBCO
Extra Details:
Water-soluble, substrate for sortase mediated labeling of proteins. Sortase catalyzes a transpeptidase reaction between a specific internal sequence of a protein and an amine group present on the N-terminus of triglycine recently has become an area of great interest. This method of labeling proteins has been denoted as “Sortagging”. Proteins conjugated to DBCO-Gly-Gly-Gly can be further modified with azide-containing molecules creating site-specific protein conjugates. Examples of creating protein conjugates using sortagging include site-specifically PEGylating proteins,1 site-specific protein-lipid conjugates,2 and constructing peptides and glycosylphosphatidylinositol chimeras.3 Sortase has also been used in peptide synthesis to cyclize peptides to create macrocyclic peptides, glycopeptides4 and protein−protein conjugates.
Molecular Weight:
598.63
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C desiccated. Avoid freeze/thaw cycles.
Type:
Buffers & General Consumables: Others