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Sulfo DBCO-TFP Ester

Product Sizes
10 mg
£230.00
CCT-1400-10MG
25 mg
£364.00
CCT-1400-25MG
100 mg
£755.00
CCT-1400-100MG
500 mg
£2485.00
CCT-1400-500MG
About this Product
SKU:
CCT-1400
Application:
Conjugation/Labeling
Extra Details:
Sulfo DBCO-TFP Ester is a water-soluble, amine-reactive labeling reagent that enables simple and efficient incorporation of Sulfo DBCO moiety onto amine-containing molecules. The hydrophilic, sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules, in many cases making them completely soluble in aqueous media. A short spacer arm adds minimal mass to modified molecules. 2,3,5,6-tetrafluorophenyl (TFP) esters is another type of carboxylic acid derivative that react with primary amines forming covalent amide bond. The amine linkage bond is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters. However, in most cases, TFP ester displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. DBCO reagents are the most commonly used substrates for copper-free click chemistry reactions. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Molecular Weight:
604.53
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C desiccated. Avoid freeze/thaw cycles.
Type:
Buffers & General Consumables: Others