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Desthiobiotin NHS Ester

Product Sizes
100 mg
£259.00
CCT-1201-100MG
500 mg
£755.00
CCT-1201-500MG
1000 mg
£1146.00
CCT-1201-1000MG
About this Product
SKU:
CCT-1201
Application:
Conjugation/Labeling
Extra Details:
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.
Molecular Weight:
311.34
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Type:
Buffers & General Consumables: Others