Cy5 Picolyl Azide
Product Sizes
1 mg
£283.00
CCT-1177-1MG
5 mg
£709.00
CCT-1177-5MG
25 mg
£1935.00
CCT-1177-25MG
About this Product
- SKU:
- CCT-1177
- Application:
- Conjugation/Labeling
- Conjugate:
- Cyanine 5
- Extra Details:
- Cy5 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported. In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol. In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging. Cy5 Picolyl Azide is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Cy5 dye is structurally similar, and spectrally is almost identical to Alexa Fluor® 647, CF® 647 Dye, or any other Cyanine5 based fluorescent dyes.
- Molecular Weight:
- 953.15 (pronated)
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C desiccated. Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
- Manufacturer's Data Sheet:Cy5-Picolyl-Azide
