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Desthiobiotin-PEG4-DBCO

Product Sizes
10 mg
£277.00
CCT-1108-10MG
25 mg
£581.00
CCT-1108-25MG
100 mg
£1624.00
CCT-1108-100MG
About this Product
SKU:
CCT-1108
Application:
Conjugation/Labeling
Extra Details:
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.
Molecular Weight:
719.87
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C desiccated. Avoid freeze/thaw cycles.
Type:
Buffers & General Consumables: Others