Bis-sulfone NHS Ester
Product Sizes
1000 mg
£525.00
CCT-1104-1000MG
5 g
£1331.00
CCT-1104-5G
About this Product
- SKU:
- CCT-1104
- Application:
- Conjugation/Labeling
- Extra Details:
- Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The covalent, site-specific conjugation of PEG to a polyhistidine tag (His-tag) on a protein with bis-alkylating reagents was also reported in literature.
- Molecular Weight:
- 597.66
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C desiccated. Avoid freeze/thaw cycles.
- Type:
- Buffers & General Consumables: Others
- Manufacturer's Data Sheet:Bis-sulfone-NHS-Ester
