mouse POU domain, class 5, transcription factor 1 (POU5F1) Adenovirus (Ad-m-Oct4)
Product Sizes
200 ul
£631.00
1792-200UL
About this Product
- SKU:
- 1792
- Additional Names:
- Ad-m-Oct4|mouse POU domain, class 5, transcription factor 1 (POU5F1) Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- Oct-3/4 is one of the family of octamer ("Oct") transcription factors, and plays a crucial role in maintaining pluripotency. The absence of Oct-3/4 in Oct-3/4+ cells, such as blastomeres and embryonic stem cells, leads to spontaneous trophoblast differentiation, and presence of Oct-3/4 thus gives rise to the pluripotency and differentiation potential of embryonic stem cells. Various other genes in the "Oct" family, including Oct-3/4's close relatives, Oct1 and Oct6, fail to elicit induction, thus demonstrating the exclusiveness of Oct-3/4 to the induction process.Using adenovirus to deliver these transcription factors has 2 main advantages - it does not incorporate into the targeted host and therefore avoids the potential for insertional mutagenesis, and the expression is transient for a brief amount of time in order for effective reprogramming to take place.This adenovirus expresses mouse Oct3/4, and it can be used in combination with other iPSC factor for the induction of iPSC reprogramming., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1792-mouse-pou-domain-class-5-transcription-factor-1-pou5f1-adenovirus
