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Proteins and Peptides

Phosphatase and tensin homolog Adenovirus (Ad-PTEN)

Product Sizes
200 ul
£631.00
1547-200UL
About this Product
SKU:
1547
Additional Names:
Ad-PTEN|Phosphatase and tensin homolog Adenovirus
Buffer:
DMEM, 2% BSA, 2.5% Glycerol
Concentration:
1E10 PFU/ml
Extra Details:
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway., vectorbiolabs
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C Avoid freeze/thaw cycles.
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles