Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) Adenovirus (Ad-PP2B/CALNA3)
Product Sizes
200 ul
£882.00
1537-200UL
About this Product
- SKU:
- 1537
- Additional Names:
- Ad-PP2B/CALNA3|Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1), calcineurin A-beta (CALNA2), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. The protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified and are designated PP1, PP2A, PP2B (calcineurin) and PP2C. The PP1 family comprises subfamily members PP1-alpha, PP1-beta and PP1-gamma. The PP2A family comprises subfamily members PP2A-alpha and PP2A-beta. The PP2B family comprises subfamily members PP2B-A-alpha, PP2B-A-beta and PP2B-A-gamma. The PP2C family comprises PP2C-alpha, PP2C-beta and PP2C-gamma. Wip1, a protein identified in the p53 DNA response pathway, has also been identified as a potential member of the PP2C family. Regulatory subunits include nuclear inhibitor of PP1 (NIPP1), PP2A-A-alpha and -A-beta, PP2A-B-alpha, -B-beta and -B-gamma, PP2A-C-alpha and -C-beta, PP2A-B56-alpha and -B56-beta, PR48 and PP2B-B1 and -B2., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1537-protein-phosphatase-3-formerly-2b-catalytic-subunit-gamma-isoform-calcineurin-a-gamma-adenovirus
