v-fos FBJ murine osteosarcoma viral oncogene homolog Adenovirus (Ad-FOS)
Product Sizes
200 ul
£882.00
1536-200UL
About this Product
- SKU:
- 1536
- Additional Names:
- Ad-FOS|v-fos FBJ murine osteosarcoma viral oncogene homolog Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- The activator protein-1 (AP-1) transcription factor consists of either Jun homodimers or Fos/Jun heterodimeric complexes, which bind the palindromic TRE sequence TGA(C/G)TCA. The Jun family includes c-Jun, Jun B and Jun D, while the Fos gene family members include c-Fos, Fos B, Fra-1 and Fra-2. In addition, certain ATF/CREB proteins form leucine zipper dimers with Fos and Jun, which exhibit different specificities for AP-1 and CRE DNA motifs. AP-1 transcription factor components are subject to regulation by both phosphorylation and by chemical oxidation of specific cysteine residues mapping within the DNA binding domains of Fos and Jun. Oxidation is reversible by a cellular redox/DNA repair protein designated Ref-1 (redox factor 1). JAB1 (Jun-activation domain-binding protein 1) potentiates transcription by either c-Jun or Jun D., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1536-v-fos-fbj-murine-osteosarcoma-viral-oncogene-homolog-adenovirus
