v-myb myeloblastosis viral oncogene homolog (avian) Adenovirus (Ad-c-Myb)
Product Sizes
200 ul
£882.00
1469-200UL
About this Product
- SKU:
- 1469
- Additional Names:
- Ad-c-Myb|v-myb myeloblastosis viral oncogene homolog (avian) Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- The Myb family of transcription factors regulate differentiation and cellular growth through binding to promoters with the consensus sequence 5'-AAC(G/T)G-3' and transactivating gene expression. The proto-oncogene c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc, and c-Myc is expressed predominantly in immature and rapidly dividing hematopoietic cells. Additional members of the family include B-Myb, a 110 kDa protein that is expressed in a wide variety of proliferating cells at the G1 to S phase transition, and A-Myb, which is expressed in reproductive tissues, some neural cells and a subset of normal and neoplastic B lymphocytes. Transactivation properties of B-Myb are apparently dependent upon the protein's hyperphosphorylation at several C-terminal residues, including Thr 447, Thr 490, Thr 497 and Ser 581. Dmp1 is related to the Myb family and also functions as a transcriptional activator. Dmp1 contains three tandem Myb repeats and is a putative substrate for cyclin D-dependent kinase., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1469-v-myb-myeloblastosis-viral-oncogene-homolog-avian-adenovirus
