Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) Adenovirus (Ad-NFKB1/p105)
Product Sizes
200 ul
£882.00
1451-200UL
About this Product
- SKU:
- 1451
- Additional Names:
- Ad-NFKB1/p105|Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1451-nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-1-p105-adenovirus
