v-raf-1 murine leukemia viral oncogene homolog 1 Adenovirus (Ad-RAF1)
Product Sizes
200 ul
£882.00
1381-200UL
About this Product
- SKU:
- 1381
- Additional Names:
- Ad-RAF1|v-raf-1 murine leukemia viral oncogene homolog 1 Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- The Raf kinases are important intermediates in signal transduction pathways. Raf-1, the prototype member of this gene family, is a 72-76 kDa cytoplasmic protein with intrinsic serine/threonine kinase activity, is broadly expressed in many cell types and is the cellular homolog of the viral oncogene, v-Raf. Other members of the Raf gene family include Raf-A and Raf-B. Raf-1 phosphorylates and thereby activates MEK (also designated MAP kinase kinase). Ras proteins bind Raf-1, but only when Ras is in its active GTP-binding state. This interaction results in Raf-mediated MEK activation. Two more recently described Raf-related proteins, Ksr-1 and Tak1 (TGFbeta-activated kinase), function as upstream regulators of Ras signaling pathways., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1381-v-raf-1-murine-leukemia-viral-oncogene-homolog-1-adenovirus
