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Proteins and Peptides

BCL2-related protein A1 Adenovirus (Ad-Bcl2A1)

Product Sizes
200 ul
£882.00
1377-200UL
About this Product
SKU:
1377
Additional Names:
Ad-Bcl2A1|BCL2-related protein A1 Adenovirus
Buffer:
DMEM, 2% BSA, 2.5% Glycerol
Concentration:
1E10 PFU/ml
Extra Details:
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival., vectorbiolabs
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C Avoid freeze/thaw cycles.
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles