PPARdelta Adenovirus (Ad-PPARd)
Product Sizes
200 ul
£631.00
1284-200UL
About this Product
- SKU:
- 1284
- Additional Names:
- Ad-PPARd|PPARdelta Adenovirus
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Concentration:
- 1E10 PFU/ml
- Extra Details:
- Peroxisome proliferator-activated receptor delta (PPARd) belongs to the nuclear receptor superfamily, which includes the steroid hormone, thyroid hormone, retinoid, and PPAR subfamilies as well as a growing number of orphan receptors. They function as ligand-dependent sequence-specific activators of transcription. When the PPAR is activated, transcription is increased. However, PPAR can also suppress a number of genes. The function of PPARs depends on the shape of their ligand-binding domain and their co-activators and co-repressors. Ligands for the PPARs include free fatty acids and eicosanoids.Three types of PPARs have been identified: alpha, gamma and delta. PPARd, identical to PPARb, is expressed in many tissues but markedly in brain, adipose tissue and skin. All PPARs dimerize with the retinoid X-receptor (RXR) and bind to PPREs (peroxisome proliferator response elements), which generally occurs in the promoter region of a gene. The GFP tagged to PPARd will allow the determination of the amount and location of PPARd expression. This adenovirus contain PPARdelta with GFP. Reference: He TC., et al., Cell. 1999 Oct 29;99(3):335-45., vectorbiolabs
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Viral Particles
- Manufacturer's Data Sheet:1284-ppardelta-adenovirus
