Vasopressin Receptor V1a (AVR-V1a) (Not for Export EU)
Product Sizes
100ul
£704.00
V2120-30-100UL
About this Product
- SKU:
- V2120-30
- Clonality:
- Polyclonal
- Extra Details:
- Rat AVR-V1a receptor is a G-protein coupled membrane protein with seven transmembrane domain. N-terminus is predicted to be extracellular. Vasopressin (AVP, Arginine-8-Vasopressin), the antidiuretic hormone is cyclic nonapeptide invovled in the homeostasis of body fluid osmolality, blood volume, vascular tone, and blood pressure. Specific actions of AVP include inhibition of diuresis, contraction of smooth muscle, stimulation of liver glycogenesis, and modulation of ACTH release from pituitary. AVP belongs to the family of vasocative and mitogenic peptide invovled in normal and pathological cell growth and differentiation. AVP receptors are members of the G-protein coupled receptors with putative 7 transmembrane domains. The sizes of various AVP receptors are V1a (rat, 424 AA; human, 418 AA); V1b (rat, 421 AA; human, 424 AA); V2 (rat, 371 AA; human 371 AA). The N-terminus and C-terminus are predicted to be extracellular and cytoplasmic, respectively. Applications: Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application. Other applications not tested. Recommended Dilution: ELISA: 1:10,000-1:50,000 Western Blot: 1:1000-1:5000 Optimal dilutions to be determined by the researcher. Control Peptide: V2120-30A Vasopressin Receptor V1a Control Peptide Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Rabbit
- Immunogen:
- A 19 amino acid peptide sequence within the extracellular, N-terminal domain of rat AVR-V1a.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, 0.05% sodium azide, 40% glycerol.
- Purity:
- Neat serum
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes rat Arginine Vasopressin Receptor V1a (AVR-V1a). The immunogen shows no significant sequence homology with AVR-V1b, AVR-V2 or AVR-V3. Species sequence homology: mouse: 84%, human 68% and sheep 52%.
- Source:
- rat
- Storage Conditions:
- 4[o]C (-20[o]C Glycerol)
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
