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Antibodies

Thyroglobulin (BSA & Azide Free) (Tg)

Product Sizes
1mg
£780.00
T5300-03A-1MG
About this Product
SKU:
T5300-03A
translate.label.attr.clone:
1.B.155
Clonality:
Monoclonal
Extra Details:
Human Thyroglobulin (Tg) is a 660kD, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobulin Tg was referred to as 'colloid'. Human Thyroglobulin (Tg) is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine. Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against human Thyroglobulin (Tg). Human Thyroglobulin Tg-specific antibodies help in the diagnosis of these diseases, but they also may be present in apparently healthy euthyroid individuals. Human Thyroglobulin (Tg) levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin (Tg) levels in the blood can also be elevated in cases of Graves disease. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: ELISA: Detection of human thyroglobulin in two-site enzyme immunoassay. Optimal dilutions to be determined by the researcher. Recommended Pair: Capture: T5300-18 Detection: T5300-03 Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Mouse
Immunogen:
Thyroglobulin from human thyroid gland.
Isotype:
IgG2b
Physical State:
Supplied as a liquid in PBS, pH 7.4. No preservative added. No stabilizing proteins added. Also available with azide. See T5300-03.
Purity:
Purified by Protein A affinity chromatography from cell culture.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes human thyroglobulin. Does not interfere with anti-thyroglobulin autoantibodies.
Source:
human
Storage Conditions:
-20[o]C
Type:
Antibodies:Sera