Synaptic adhesion-like molecule 2 (SALM2, LRFN1, leucine rich repeat and fibronectin type III domain containing 1, KIAA1484, Leucine-rich repeat and fibronectin type III domain-containing protein 1)
Product Sizes
100ug
£825.00
S9111-04-100UG
About this Product
- SKU:
- S9111-04
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Synaptic adhesion-like molecule 2 (SALM2; also leucine-rich repeat and fibronectin type-III domain-containing protein 1 (Lrfn1) is a 105kD member of the Lrfn family of type I transmembrane glycoproteins. Human SALM2 is synthesized as a 771aa precursor that contains a 31aa signal sequence, a 505aa extracellular domain, a 21aa transmembrane region, and a 214aa cytoplasmic region. The ECD consists of seven leucine-rich repeats, an IgC2-like domain, and a fibronectin type-III domain, tandemly aligned in that order. In addition, there are two potential sites for N-linked glycosylation. The C-terminal region contains an intracellular PDZ binding domain, which is conserved among SALMs 1-3, but is absent in SALMs 4 and 5. Mature human SALM2 shares 96% and 95% sequence identity with mature mouse and rat SALM2, respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Sheep
- Immunogen:
- CHO cell-derived recombinant human SALM2.
- Isotype:
- IgG
- Physical State:
- Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
- Purity:
- Purified by immunoaffinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human SALM2. Cross-reactivity: SALM3 (<5%), SALM4 (<5%). Species sequence homology: mouse (96%), rat (95%).
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
