Survivin (TIAP, API4)
Product Sizes
1mg
£812.00
S8500-08A-1MG
About this Product
- SKU:
- S8500-08A
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Survivin is a 16kD apoptosis inhibitor protein (IAP). It binds and inhibits the caspase-3 proteolytic activity and controls the checkpoint in the G2/M phase of the cell cycle to promote cell division by the control of microtubule stability and assembly of a normal mitotic spindle. Survivin is highly expressed during fetal development, transformed cell lines, human cancers and non-Hodgkin's lymphomas. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:50 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide (EETAKKVRRAIEQLAAMD) corresponding to aa125-142 of human Survivin
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.2.
- Purity:
- Purified by Protein G affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Survivin
- Source:
- human
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies:Polyclonal Antibody
