Securin, Recombinant, Human (Cut2, ESP1-associated Protein 1, EAP1, hPTTG, MGC126883, MGC138276, Pds1, Pituitary Tumor Transforming 1, PTTG, PTTG1, TUTR1)
Product Sizes
100ug
£576.00
S0379-80B-100UG
About this Product
- SKU:
- S0379-80B
- Extra Details:
- PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles; the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human PTTG1, aa1-202, His-tagged, expressed in E. coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 24.1
- Physical State:
- Supplied as liquid in 20mM Tris-HCl buffer, pH8.0 0.1 M NaCl, 10% glycerol
- Purity:
- ~80% by SDS-PAGE Purified by immunoaffinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
