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Antibodies

Rabies

Product Sizes
100ug
£249.00
R0012-100UG
About this Product
SKU:
R0012
Application:
Immunohistochemistry, Immunofluorescence
translate.label.attr.clone:
1.B.456
Clonality:
Monoclonal
Extra Details:
Rabies virus is a Lyssavirus that causes rabies in mammals. The virus is found in the saliva of infected animals and is mostly spread though bites. The virus then travels though the peripheral nervous system to the central nervous system. Once it reaches the brain it causes acute encephalitis. Symptoms include paralysis, cerebral dysfunction, anxiety, insomnia, confusion, anger, paranoia, terror and hallucination. The production of a large amount of saliva, the inability to speak or swallow and associated hydrophobia is also common in the later stages of the disease. The time between exposure to the virus and onset of symptoms can range from about 2 weeks to several months. Once symptoms appear, death is virtually inevitable. However, the disease can be effectively treated by post-exposure prophylaxis, through vaccination, provided this is done as soon as possible. Applications: Suitable for use in Immunofluorescence, Indirect ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed paraffin embedded sections. Optimal dilutions to be determined by the researcher. Titer: Immunofluorescence: >1x10e3 (Titer by Native BHK) Indirect ELISA: 1.5x10e6 (Titer by Indirect ELISA) Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Mouse
Immunogen:
Purified rabies virus.
Isotype:
IgG2a
Physical State:
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Purity:
Purified by Protein A affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes a glycoprotein of more than 20 different strains of rabies virus from 4 serogroups: CVS, Lagosbat, Mokola, Duwenhage were positive in neutralization reaction.
Storage Conditions:
-20[o]C
Type:
Antibodies:Monoclonal Antibody