Prostate Stem Cell Antigen (PSCA, HGNC:9500, PRO232)
Product Sizes
100ug
£512.00
P9054-61H-100UG
About this Product
- SKU:
- P9054-61H
- Clonality:
- Polyclonal
- Extra Details:
- PSCA (Prostate Stem Cell antigen) is a cell surface antigen which is overexpressed in ~40% of primary prostate cancers and in nearly 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical xenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Goat
- Immunogen:
- Synthetic peptide with sequence KAQVSNEDCLQVEN, from the internal region of human PSA.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
- Purity:
- Purified by affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human PSA.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
