PGPEP1 (Pyroglutamyl-peptidase 1, 5-oxoprolyl-peptidase, Pyroglutamyl Aminopeptidase I, PAP-I, Pyroglutamyl-peptidase I, PGP-I, Pyrrolidone-carboxylate Peptidase, PGPI)
Product Sizes
100ug
£876.00
P3365-15-100UG
About this Product
- SKU:
- P3365-15
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Pyroglutamyl peptidase-1 is an omega peptidase which removes pyroglutamyl residues from the amino termini of peptides and proteins. It is a cytosolic cysteine peptidase that is expressed in most cell types. The enzyme requires a thiol-reducing agent for activity. PGPEP-1 is potentially involved in the inactivation of biologically active peptides that possess an a terminal pyroglutamyl group. Examples of such peptides include neurotensin, luteinizing hormone releasing hormone, and thyrotropin-releasing hormone. Human and mouse PGPEP-1 share 95%aa sequence identity. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Sheep
- Immunogen:
- Recombinant protein corresponding to aa1-209 from human PGPEP-1 expressed in E.coli.
- Isotype:
- IgG
- Physical State:
- Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
- Purity:
- Purified by immunoaffinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human PGPEP-1.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
