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Antibodies

Parkin (Ubiquitin-protein Ligase E3) (epitope b)

Product Sizes
1mg
£812.00
P3112-04A-1MG
About this Product
SKU:
P3112-04A
Application:
Western Blot
Clonality:
Polyclonal
Extra Details:
Parkin is a ubiquitin-protein ligase (E3) involved in the ubiquitin proteasomal pathway by participating in the removal of abnormally folded or damage protein. It is highly expressed in the brain, including the substancia nigra, and is also expressed in other tissues (heart, testis, skeletal muscle). Mutations in the parkin gene causing loss of E3 activity are responsible for autosomal recessive juvenile Parkinson's desease. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Rabbit
Immunogen:
Synthetic peptide (NATGGDDPRNAAGGCERE) corresponding to aa81-98 of human Parkin
Isotype:
IgG
Physical State:
Supplied as a liquid in PBS, pH 7.2.
Purity:
Purified by Protein G affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes human Parkin
Source:
human
Storage Conditions:
-20[o]C
Type:
Antibodies:Polyclonal Antibody