NFkB, p65, NLS Specific (NF-kB, Nuclear Factor kappa B, RelA)
Product Sizes
100ug
£639.00
N2303-02A-100UG
About this Product
- SKU:
- N2303-02A
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- P65 NLS is a transcription factor belonging to NF-kappa B family with the N-terminal Rel homology domain of the NF-kB family, a C-terminal transcription activation domain and a nuclear receptor interaction motif (LXXLL). p65 is a part of the nuclear localization signal (NLS) polypeptide of NF-kB (p50/p65) heterodimer. IkBa the most abundant IkB interacts with active NF-kB p65 homodimers and inactivates their transcriptional potential by trapping them in the cytoplasm and through stable complex formation. It is ubiquitously expressed in most of the tissues. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1-3ug/ml Immunocytochemistry: 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- A portion of the NF-kB p65 nuclear localization signal (DTDDRHRIEEKRKRKT).
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
- Purity:
- Purified by immunoaffinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human NFkB, p65, NLS Specific. Species Crossreactivity: bovine, chimpanzee, gorilla, equine, monkey and mouse.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies:Polyclonal Antibody
