a2-Macroglobulin, Human (alpha-2-Macroglobulin, A2M, alpha 2M, CPAMD5, FWP007, S863-7)
Product Sizes
1mg
£709.00
M1150-05-1MG
About this Product
- SKU:
- M1150-05
- Extra Details:
- A2M is a large plasma protein found in the blood and is produced by the liver. It is a major component of the alpha-2 band in protein electrophoresis. Levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins. Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter, inhibiting many proteases, including trypsin, thrombin and collagenase, and is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. Molecular Weight: ~725kD Protein: Reported in mg/vial (A280nm, E0.1%=0.81) Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 725
- Physical State:
- Supplied as a lyophilized powder from 30mM sodium phosphate, pH 6.5, 1mg glycine. Reconstitute with 1ml sterile ddH2O.
- Purity:
- ≥95% (SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Type:
- Biomaterials:Blood Products
