Ly49F (Klra6, Killer Cell Lectin-like Receptor, subfamily A, member 6, Killer Cell lectin-like receptor 6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F)
Product Sizes
500ug
£531.00
L7732-25-500UG
About this Product
- SKU:
- L7732-25
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- 5K30 (HBF-719)
- Clonality:
- Monoclonal
- Extra Details:
- The B6 allele of Ly49F is a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤1ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- CHO cells transfected with the B6 allele of Ly49F
- Isotype:
- IgG1,k
- Physical State:
- Supplied as a liquid in 100mM borate buffered saline, pH 8.2.
- Purity:
- Purified
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes the B6 allele of the mouse Ly49F receptor. Stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month-old) to 10.0% (11 month-old) of CD8+ spleen cells from C57BL/6 mice.
- Source:
- mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
