KIR2DL1, Recombinant, Human, aa23-223 (p58 KIR, p58.1, CD158, cl-42, KIR-K6, NKAT1, NKR-K6, Killer Cell Immunoglobulin (Ig)-like Receptor)
Product Sizes
100ug
£576.00
K1858-40-100UG
About this Product
- SKU:
- K1858-40
- Extra Details:
- An inhibitory Killer Cell Ig-like Receptor (KIR, previously called p58 KIR, p58.1, cl-42, NKAT1, or KIR-K6), which recognizes class I MHC molecules (HLA-Cw2, -Cw4, -Cw5, and Cw6). The protein coding region of the extracellular domain of KIR2DL1 (amino acids 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DL1 was overexpressed as insoluble protein aggregates(inclusion bodies). Recombinant protein corresponding to aa23-223 from human KIR2DL1, expressed in E. coli. Molecular Weight: ~22.2kD (202aa) confirmed by MALDI-TOF Amino Acid Sequence: MEGVHRKPSL LAHPGRLVKS EETVILQCWS DVMFEHFLLH REGMFNDTLR LIGEHHDGVS KANFSISRMT QDLAGTYRCY GSVTHSPYQV SAPSDPLDIV IIGLYEKPSL SAQLGPTVLA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAGPKVNGTF QADFPLGPAT HGGTYRCFGS FHDSPYEWSK SSDPLLVSVT GN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molecular Weight:
- 22.2
- Physical State:
- Supplied as a liquid in 20mM Tris-HCl, pH 7.5.
- Purity:
- ≥95% by SDS PAGE. Purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Type:
- Biomaterials:Blood Products
