Isoprostane (8-iso-PGF2a)
Product Sizes
100ug
£620.00
I9050-50-100UG
About this Product
- SKU:
- I9050-50
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Extra Details:
- Isoprostanes are prostaglandin-like compounds that are produced by free radical mediated peroxidation of lipoproteins. Levels of 15-isoprostane F2t in biological fluids have been shown to be useful for assessment of oxidant stress in vivo. 15- isoprostane F2t has also been shown to be a potent vasoconstrictor in rat kidneys and rabbit lungs, and plays a causative role in atherogenesis. Elevated isoprostane levels are associated with hepatorenal syndrome, rheumatoid arthritis, atherosclerosis, and carcinogenesis. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Goat
- Immunogen:
- Synthetic 8-epi-PGF2a.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in TBS.
- Purity:
- Purified by ammonium sulfate precipitation.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes 8-epi-PGF2a. Cross-Reactivity: 9a,11b-PGF2a: 4.1%; 13,14-dihydro-15-keto-PGF2a: 3.0%; 9b,11a-PGF2alphaa: <0.01%; PGF1alpha1a: <0.01%; 6-keto-PGF1alpha1a: <0.01%; PGE2: <0.01%; PGD2: <0.01%; Arachidonic Acid: <0.01%.
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
