Interleukin 13 (IL-13) (Azide Free)
Product Sizes
500ug
£607.00
I8435-05AX-500UG
About this Product
- SKU:
- I8435-05AX
- translate.label.attr.clone:
- JES10-5A2
- Clonality:
- Monoclonal
- Extra Details:
- IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1b, TNF-a, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: ELISA: Capture Optimal dilutions to be determined by the researcher. Matched Pair (Sandwich): Capture: I8435-05AX Detection: 228224 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rat
- Immunogen:
- Recombinant corresponding to human Interleukin 13 expressed in COS cells.
- Isotype:
- IgG1,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.4. No preservative added.
- Purity:
- Purified. Endotoxin: ≤0.05EU/ug (LAL).
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Interleukin-13 (IL-13).
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
