Interleukin 8 (IL-8)
Product Sizes
100ug
£748.00
I8430-02N-100UG
About this Product
- SKU:
- I8430-02N
- Application:
- Western Blot
- translate.label.attr.clone:
- 7H106
- Clonality:
- Monoclonal
- Extra Details:
- CXCL8, also known as IL-8, is a chemoattractant that recruits neutrophils to sites of inflammation, activates neutrophil functions and promotes angiogenesis. CXCL8 production is rapidly induced by pro-inflammatory signals in many different cell types. The biological activites of CXCL8 are mediated by chemokine receptors CXCR1 and CXCR2. Feline CXCL8 is translated as a 101 aa precursor protein with a 22 aa signal peptide. It shares 61% and 76% aa sequence identity with human and canine CXCL8, respectively. Applications: Suitable for use in Western Blot, Neutralization and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml ELISA: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Rat
- Immunogen:
- E.coli-derived recombinant feline CXCL8 (aa23-101) Accession # AAD40323
- Isotype:
- IgG2b
- Physical State:
- Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Purity:
- Purified by Protein G affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes feline CXCL8.
- Source:
- feline
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
