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Proteins and Peptides

Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine, T-cell Growth Factor, TCGF)

Product Sizes
10ug
£338.00
I7663-26-10UG
About this Product
SKU:
I7663-26
Extra Details:
Interleukin-2 is a potent immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Human IL-2 is a 15.5kD protein containing 134 amino acid residues including one intrachain disulfide bond. Recombinant protein corresponding to human Interleukin-2 expressed in E. coli. Biological Activity: The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is ≤0.1ng/ml, corresponding to a specific activity of ≥ 1x10e7u/mg. AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with acetic acid. For long term storage add 0.1% carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
15.5
Physical State:
Supplied as a lyophilized powder from 10mM sodium citrate, pH 4.0. Reconstitute in 100mM acetic acid to a concentration of 0.1-1.0mg/ml. For long term storage add 0.1% carrier protein.
Purity:
≥98% (SDS-PAGE, HPLC) Endotoxin: ≤0.1ng/ug
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins