Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla, ITGB1, Fibrinogen Receptor beta Subunit, FNRB, Integrin VLA4 Subunit beta, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLAB, VLAbeta) (FITC)
Product Sizes
100ug
£620.00
I7661-38R3-100UG
About this Product
- SKU:
- I7661-38R3
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- HM beta 1-1
- Clonality:
- Monoclonal
- Extra Details:
- The integrin beta 1 subunit (CD29) is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leukocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: Spleen cells from immunized Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Hamster
- Immunogen:
- Purified mouse VLA-4 antigen.
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes the murine integrin beta 1 subunit. Inhibits beta 1 integrin mediated adhesion. Species Crossreactivity: rat.
- Source:
- mouse
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
