Insulin
Product Sizes
1mg
£896.00
I7656-06-1MG
About this Product
- SKU:
- I7656-06
- translate.label.attr.clone:
- 1.B.105
- Clonality:
- Monoclonal
- Extra Details:
- Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B-cell origin such as insulinoma. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Recommended Pair: Matched to I7656-07 as the detection or conjugate (label) antibody. Detection: I7656-06 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Purified human insulin.
- Isotype:
- IgG1,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. No glycerol added.
- Purity:
- Purified by Protein A affinity chromatography (>90%, SDS-PAGE).
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Insulin. Does not crossreact wtih free C-peptide. Species Crossreactivity: human proinsulin, bovine insulin (30%) and porcine insulin.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
