13S-Hydroxyoctadecadienoic Acid (13S-HODE)
Product Sizes
50ug
£397.00
H9110-17-50UG
About this Product
- SKU:
- H9110-17
- Application:
- Immunohistochemistry, Radioimmunoassay
- Clonality:
- Polyclonal
- Extra Details:
- 13(S)-HODE (13(S)-hydroxyoctadecadienoic acid) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1uM (refs 1 and 2) and down regulation of IRGpIIb/IIIa receptor expression (ref 3). 13(S)-HODE methyl ester is a neutral, more lipophilic form of the free acid that can been used as an analytical standard for 13(S)-HODE. Applications: Suitable for use in RIA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: RIA: 2ug/well Optimum dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Goat
- Immunogen:
- 13(S)-Hydroxyoctadecadienoic Acid
- Isotype:
- IgG
- Physical State:
- Supplied as liquid in PBS.
- Purity:
- IgG fraction
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes 13(S)-HODE: 100.0%. Crossreactivity: 13(R)-HODE: 11.7%; 9-oxo-ODE: 11.7%; 15(S)-HETE: 6.0%; 11(S)-HETE: 2.7%; 9(R)-HODE: 0.8%; 9(S)-HODE: 0.6%; Linoleic Acid: 0.5%; 13-oxo-ODE: 0.4%.
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Polyclonal Antibody
