Galanin Receptor 1 (GALR1) (Not for Export EU)
Product Sizes
100ul
£704.00
G1043-05A-100UL
About this Product
- SKU:
- G1043-05A
- Clonality:
- Polyclonal
- Extra Details:
- Galanin is a 29aa C-terminally amidated (30aa, non-amidated in humans), highly conserved but unique neuroendocrine peptide originally isolated from intestine. The first 14aa are fully conserved in almost all species. Galanin is found in the brain and the gut. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. Several N-terminally elongated (-7-29 and -9-29) or truncated biologically active forms of galanin have also been isolated. Galanin antagonists are chimeric peptides generated by linking the amino terminal portion of galanin to substance P (galantide, M15), bradykinin (M35), the neurokinin antagonist spantide (C7) or an idealized alpha helical region (M40) (see review in refs 2 by Kask et al 1995). Galanin mediated its biological effects by interacting with high affinity cell surface G-protein coupled receptors (GALR1-3). Applications: Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application. Other applications not tested. Recommended Dilution: ELISA: 1:10-1:1000,000 (Coat with 50-100ng Control Peptide/well). Western Blot: 1:1000-1:5,000 Optimal dilutions to be determined by the researcher. Recommended Control Peptide: G1043-05H: Galanin Receptor 1, Mouse (GALR1) (Control Peptide) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Rabbit
- Immunogen:
- A synthetic 22 aa peptide sequence within the cytoplasmic region, C-terminus of mouse GLAR1, (KLH). Species sequence homology: human (90%) and rat (76%).
- Isotype:
- IgG
- Physical State:
- Supplied as a liquid in PBS, 0.05% sodium azide.
- Purity:
- Serum
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes mouse Galanin Receptor 1. No significant homology is seen with GLAR2, GALR3 or any other G-protein coupled receptors.
- Source:
- mouse
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies:Polyclonal Antibody
