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Proteins and Peptides

Fibroblast Growth Factor, Basic, Recombinant, Human, 154aa (FGF2, BFGF, FGFB, HBGF-2, HBGH-2, Heparin-binding Growth Factor 2 Precursor, Prostatropin)

Product Sizes
50ug
£492.00
F4210-10G-50UG
About this Product
SKU:
F4210-10G
Extra Details:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2kD protein consisting of 154 amino acid residues. Recombinant protein correponding to human Fibroblast Growth Factor, Basic expressed in E. coli. Molecular Weight: ~17.2kD Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1ng/ml, corresponding to a specific activity of ≥1x10e7 units/mg. Amino Acid Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
17.2
Physical State:
Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O to ≥0.1mg/ml.
Purity:
≥95% (RP-HPLC, SDS-PAGE). Endotoxin: ≤0.1ng/ug (≤1EU/ug)
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins