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Antibodies

Cytokeratin 19

Product Sizes
50ug
£832.00
C9097-28-50UG
About this Product
SKU:
C9097-28
Application:
Western Blot, Immunohistochemistry
translate.label.attr.clone:
5F230 (Ks19.2 (Z105.6))
Clonality:
Monoclonal
Extra Details:
Tumors Specifically Detected: All tested adenocarcinoma; cholangio carcinoma of liver; renal cell carcinoma; transitional cell carcinoma of the bladder; ovary carcinoma; squamous cell carcinoma of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast carcinoma and thymoma. Represents an excellent marker to discriminate glandular epithelial carcinoma from those of different origin. No reaction with hepatocellular carcinoma. Applications: Suitable for use in ELISA, Western Blot, Immunocytochemistry and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (Frozen): 1:10 with PBS, pH 7.4. Incubate for 1 hr at RT. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Host:
Mouse
Immunogen:
Cytokeratin 19 from MCF-7 cells. Epitope: aa352-368 (VRADSERQNQEYQRLMD) of the a-helical fragment.
Isotype:
IgG2b
Physical State:
Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Purity:
Purified by Protein A affinity chromatography.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes human Cytokeratin 19 at ~40kD on human glandular epithelia. Species Crossreactivity: rat, fish, bovine, rabbit. Does not react with mouse, woodchuck, chicken or Xenopus. Reactive with cultured cell lines: MCF-7, RT 112, Detroit 562, RPMI 2650, HT-29 and SSC-12. Detected Cytokeratin 19 in cholangio carcinoma of liver, renal cell carcinoma, transitional cell carcinoma of the bladder, ovar
Source:
human
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Antibodies:Monoclonal Antibody