Cystatin C (AD8, Amyloid Angiopathy and Cerebral Hemorrhage, Cst3, Cystatin 3, Gamma Trace, HCCAA, Neuroendocrine Basic Polypeptide, Post gamma Globulin, ARMD11, MGC117328, OTTHUMP00000030440, OTTHUMP00000164181, bA218C14.4)
Product Sizes
1mg
£1215.00
C8950-01B-1MG
About this Product
- SKU:
- C8950-01B
- translate.label.attr.clone:
- 7E112
- Clonality:
- Monoclonal
- Extra Details:
- Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medical and evolutionary points of view. Cystatin C, with molecular weight of 13,260D, is composed of 146 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Matched Pairs: Capture: C8950-03, C8950-09C Detection: C8950-01B Hybridoma: Sp 2/0 myeloma cells with spleen cells of Balb/c mice. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Mouse
- Immunogen:
- Human Cystatin C conjugated with BSA
- Isotype:
- IgG1
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
- Purity:
- Purified by Protein A affinity chromatography from ascites.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Cystatin C.
- Source:
- human
- Storage Conditions:
- 4[o]C Do not freeze
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
