CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)
Product Sizes
100ug
£850.00
C8350-07-100UG
About this Product
- SKU:
- C8350-07
- Application:
- Flow Cytometry, Immunohistochemistry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- 6A57 (12G5)
- Clonality:
- Monoclonal
- Extra Details:
- Viral entry into target cells is mediated through a complex interaction between the viral envelope protein and specific cellular receptors. The CD4 glycoprotein is the primary receptor for human HIV types 1 and 2. However, one or more cellular coreceptors are also needed for viral entry. CXCR4 has been identified as a co-receptor for HIV type 1. T lymphocytes and macrophages in both lymphoid and non-lymphoid tissues are the major cell populations expressing CXCR4. CXCR4, also known as Chemokine (C-X-C motif) Receptor 4 or CD184, is a receptor for the CXC chemokine stromal cellderived factor-1 (SDF-1) and is involved in cardiogenesis, blood vessel formation, and cerebellular development. CXCR4 has been reported to be ubiquitously expressed in blood and tissue cells. Applications: Suitable for use in Western Blot, Immunofluorescence, Immunohistochemistry and Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Western Blot: 2ug/ml Flow Cytometry: 3-5ug/ml Optimal dilutions to be determined by the researcher. Positive Controls: Human lymphoid cell lines, human liver and brain tissues. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- SIV infected Sup-T1 cells injected into Balb/c mice
- Isotype:
- IgG2a,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
- Purity:
- Purified by Protein A affinity chromatography
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human CXCR4 protein.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
