CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184) (MaxLight 550)
Product Sizes
100ul
£1106.00
C8350-07-ML550-100UL
About this Product
- SKU:
- C8350-07-ML550
- Application:
- Flow Cytometry, Immunohistochemistry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- 6A57 (12G5)
- Clonality:
- Monoclonal
- Extra Details:
- Viral entry into target cells is mediated through a complex interaction between the viral envelope protein and specific cellular receptors. The CD4 glycoprotein is the primary receptor for human HIV types 1 and 2. However, one or more cellular coreceptors are also needed for viral entry. CXCR4 has been identified as a co-receptor for HIV type 1. T lymphocytes and macrophages in both lymphoid and non-lymphoid tissues are the major cell populations expressing CXCR4. CXCR4, also known as Chemokine (C-X-C motif) Receptor 4 or CD184, is a receptor for the CXC chemokine stromal cellderived factor-1 (SDF-1) and is involved in cardiogenesis, blood vessel formation, and cerebellular development. CXCR4 has been reported to be ubiquitously expressed in blood and tissue cells. Applications: Suitable for use in Immunohistochemistry, Western Blot, Immunofluorescence and Flow Cytometry. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: 10ug/ml Immunofluorescence: 10ug/ml. Do not use cells fixed in acetone or methanol. 3% paraformaldehyde has been shown to give optimal results. Flow Cytometry: 2-5ug/ml Optimal dilutions to be determined by the researcher. Positive Controls: Human lymphoid cell lines, human liver and brain tissues. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Host:
- Mouse
- Immunogen:
- SIV infected Sup-T1 cells injected into Balb/c mice
- Isotype:
- IgG2a,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™550.
- Purity:
- Purified by Protein A affinity chromatography
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human CXCR4 protein.
- Source:
- human
- Storage Conditions:
- 4[o]C Do Not Freeze
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
