CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184) (HRP)
Product Sizes
100ul
£1106.00
C8350-07-HRP-100UL
About this Product
- SKU:
- C8350-07-HRP
- Application:
- Western Blot, Immunohistochemistry
- translate.label.attr.clone:
- 6A57 (12G5)
- Clonality:
- Monoclonal
- Extra Details:
- Viral entry into target cells is mediated through a complex interaction between the viral envelope protein and specific cellular receptors. The CD4 glycoprotein is the primary receptor for human HIV types 1 and 2. However, one or more cellular coreceptors are also needed for viral entry. CXCR4 has been identified as a co-receptor for HIV type 1. T lymphocytes and macrophages in both lymphoid and non-lymphoid tissues are the major cell populations expressing CXCR4. CXCR4, also known as Chemokine (C-X-C motif) Receptor 4 or CD184, is a receptor for the CXC chemokine stromal cellderived factor-1 (SDF-1) and is involved in cardiogenesis, blood vessel formation, and cerebellular development. CXCR4 has been reported to be ubiquitously expressed in blood and tissue cells. Applications: Suitable for use in Immunohistochemistry and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Positive Controls: Human lymphoid cell lines, human liver and brain tissues. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Host:
- Mouse
- Immunogen:
- SIV infected Sup-T1 cells injected into Balb/c mice
- Isotype:
- IgG2a,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with horseradish peroxidase (HRP).
- Purity:
- Purified by Protein A affinity chromatography
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human CXCR4 protein.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
