Complement C3a (C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 1, C3, Complement C3 alpha Chain, CPAMD1) (APC)
Product Sizes
100Tests
£806.00
C7850-13L-100TESTS
About this Product
- SKU:
- C7850-13L
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- 11C9
- Clonality:
- Monoclonal
- Extra Details:
- Complement Component 3a receptor (C3a R) is an ~90kD G protein-coupled 7 transmembrane sulfated glycoprotein expressed on myeloid peripheral blood leukocytes, and on activated lymphocytes, endothelial and internal organ epithelial cells. Engagement of C3a R by C3a activates mast cells and neutrophils, triggering degranulation in airways during asthmatic allergen challenges. It assists in Th2-type inflammatory reactions and stimulates leukocyte chemotaxis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- NS0 mouse myeloma cell line transfected with human C3a R Met1-Val482.
- Isotype:
- IgG2a
- Physical State:
- Supplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Purity:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Complement C3a R.
- Source:
- human
- Storage Conditions:
- 4[o]C Do Not Freeze
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
