Choline Acetyltransferase (CHAT)
Product Sizes
100ul
£704.00
C5057-09-100UL
About this Product
- SKU:
- C5057-09
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- 2Q28 (1E6)
- Clonality:
- Monoclonal
- Extra Details:
- Acetylcholine (Ach) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransfrase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-cholinacetyltransferase a useful specific marker. Applications: Suitable for use in Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 1:100-1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Choline acetyltransferase purified from rat brain
- Isotype:
- IgG1
- Physical State:
- Supplied as a liquid.
- Purity:
- Ascites
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes rat cholinergic neurons in the brain and central nervous system. Reported to crossreact with chicken and human.
- Source:
- rat
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
