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Antibodies

CD91, 515kD (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein)

Product Sizes
1mg
£1106.00
C2441-95D-1MG
About this Product
SKU:
C2441-95D
Application:
Flow Cytometry, Immunohistochemistry, Western Blot
translate.label.attr.clone:
MA8G1
Clonality:
Monoclonal
Extra Details:
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Applications: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Host:
Mouse
Immunogen:
Human 515kD low density LRP.
Isotype:
IgG1,k
Physical State:
Supplied as a liquid in PBS, pH 7.4.
Purity:
Purified by Protein A affinity chromatography from ascites.
Shipping Conditions:
Blue Ice
Specificity:
Recognizes the human heavy chain 515kD low density lipoprotein receptor-related protein (LRP).
Source:
human
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Antibodies:Monoclonal Antibody