CD51 (Integrin alpha-V, Vitronectin Receptor alpha Chain, ITGAV, MSK8, VNRA) (PE)
Product Sizes
100Tests
£639.00
C2405-11R-PE-100TESTS
About this Product
- SKU:
- C2405-11R-PE
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- NKI-M9
- Clonality:
- Monoclonal
- Extra Details:
- CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor alpha chain, or integrin alphaV. It forms heterodimer with integrin beta1 (CD29), beta3 (CD61), beta5, beta6, or beta8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its beta chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 5ul/10e6 cells in 100ul staining volume or 5ul per 100ul of whole blood. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Melonama cells
- Isotype:
- IgG2a,k
- Physical State:
- Supplied as a liquid in PBS, pH 7.2, BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Purity:
- Purified by affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human CD51.
- Source:
- human
- Storage Conditions:
- 4[o]C Do Not Freeze
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
