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Antibodies

CD45RC (Leukocyte Common Antigen HMW, LCA, Ly-5 T200) (Biotin)

Product Sizes
500ug
£607.00
C2400-59N-500UG
About this Product
SKU:
C2400-59N
Application:
Immunoprecipitation, Flow Cytometry
translate.label.attr.clone:
C455.1F
Clonality:
Monoclonal
Extra Details:
The CD45 family of cell-surface glycoprotein antigens exist as a set of isoforms.1-4 The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T-200 species.1-4 The “restricted” subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells.1 Applications: • Identification and enumeration of CD45RC+ cells by flow cytometry • Immunoprecipitation Recommended Dilution: Flow Cytometry: ≤ 1ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Host:
Rat
Isotype:
IgG2a,k
Physical State:
Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin.
Purity:
Purified
Shipping Conditions:
Blue Ice
Specificity:
Recognizes an exon C-dependent epitope of CD45 glycoprotein.
Source:
mouse
Storage Conditions:
-20[o]C
Supplier:
United States Biological
Type:
Antibodies:Monoclonal Antibody