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Antibodies

CD45R (Leukocyte Common Antigen, LCA, Ly-5 T200) (PE/CY5)

Product Sizes
100ug
£448.00
C2400-26R5-100UG
About this Product
SKU:
C2400-26R5
Application:
Flow Cytometry, Immunohistochemistry
translate.label.attr.clone:
RA3-6B2
Clonality:
Monoclonal
Extra Details:
CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤0.2ug/10e6 cells Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE/Cy5 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Host:
Rat
Immunogen:
Abelson murine leukemia virus-induced pre-B tumor cells
Isotype:
IgG2a,k
Physical State:
Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with R-Phycoerythrin PE/CY5.
Purity:
Purified
Shipping Conditions:
Blue Ice
Specificity:
Recognizes B220 isoform of mouse CD45, Mr 240kD. Species Crossreactivity: mouse and feline
Source:
mouse
Storage Conditions:
4[o]C Do Not Freeze
Type:
Antibodies:Monoclonal Antibody