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Proteins and Peptides

Cathepsin H, Recombinant, Human, aa23-335, His-Tag (CTSH, Cathepsin H Mini Chain, Cathepsin H Heavy Chain, Cathepsin H Light Chain, CPSB)

Product Sizes
10ug
£951.00
C2097-62-10UG
About this Product
SKU:
C2097-62
Extra Details:
Cathepsin H is a lysosomal cysteine protease of the papain family. It is synthesized as a precursor protein that is proteolytically processed to a mature form consisting of a light chain, a heavy chain, and a minichain. Cathepsin H is the only known monoaminopeptidase in the papain family. Cathepsin H is primarily an aminopeptidase, but also functions as an endopeptidase. Cathepsin H is potently inhibited by cystatins A, B, and C and by ovocystatin. Cathepsin H expression is altered in disease states such as prostate and colorectal cancers. Source: Recombinant corresponding to aa23-335 from human Cathepsin H fused to 10-His-tag at C-terminal expressed in CHO cell line. Molecular Weight: ~37kD Biological Activity: Measured by its ability to cleave the fluorogenic peptide substrate, Arg7amido4methylcoumarin (RAMC). Specific Activity: >750 pmol/min/ug, as measured under the described conditions. Endotoxin: ~1EU/1ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
37
Physical State:
Supplied as a liquid in Tris, sodium chloride. BSA free.
Purity:
~80% (SDS-PAGE)
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
United States Biological
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins