Caspase 9 (APAF, ICE-LAP6, MCH6)
Product Sizes
200ug
£594.00
C2088-04-200UG
About this Product
- SKU:
- C2088-04
- Application:
- Western Blot
- translate.label.attr.clone:
- 3C122 (LAP6 96-2-22)
- Clonality:
- Monoclonal
- Extra Details:
- Caspases are cysteine proteases, expressed as inactive precursors. Caspases mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis: initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Active human kidney 293 cell lysates. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Recombinant human Caspase 9 pro-domain protein.
- Isotype:
- IgG1,k
- Physical State:
- Supplied as a liquid in PBS, 0.02% sodium azide.
- Purity:
- Purified by Protein G affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes human Caspase 9.
- Source:
- human
- Storage Conditions:
- -20[o]C
- Supplier:
- United States Biological
- Type:
- Antibodies:Monoclonal Antibody
